pycnogenol benefits dr axe

", American Heart Association: Understanding Blood Pressure Readings., Iranian Journal of Public Health: "Effect of Pycnogenol Supplementation on Blood Pressure: A Systematic Review and Meta-analysis. The first studied group included 66 healthy subjects in whom the number of muscle cramps was recorded two weeks before entering the study and during the fourth and fifth week. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. SelfDecode is a personalized health report service, It can also stabilize mast cells, which release histamine and trigger allergic reactions. Pycnogenol treatment reduced the need for painkillers by 58% versus one percent in the placebo-treated group. PQQ (pyrroloquinoline quinone), also called methoxatin, is a vitamin-like compound that exists naturally in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk . Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. This nerve affects our balance and hearing by sending signals to the brain. (7). Pycnogenol is the registered trademark brand name of French maritime pine bark extract. Taking pine bark extract supports healthy blood pressure. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. The treatment was four 50 mg capsules of Pycnogenol. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . Learn about this tree-based pill and how it might be able to help you. Its used as a natural supplement for several conditions, including dry skin and ADHD. Pycnogenol; Pycnogenol. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Take Helpful Supplements. ", Journal of Medicinal Food: "Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine Bark, Pycnogenol. Arginine is a non-essential amino acid because most humans can make it in their bodies. DOI: Gulati OP. For mild high blood pressure: 200 milligrams daily. The studies revealed that the sperm concentration greatly increased after about eight to 16 weeks of treatment, to include improved orgasmic function. While OPCs found in this extract are mostly known for their antioxidant-producing benefits, these amazing compounds exude antibacterial, antiviral, anticarcinogenic, anti-aging, anti-inflammatory and anti-allergic properties. . Tell your doctor about any supplements you're taking, even if they're natural. Top 9 Natural Allergy Relief Home Remedies - Dr. Axe 1 week ago from draxe.com Eat an Anti-Inflammatory, Alkaline Diet. Pycnogenol treatment resulted in more normal-looking sperm. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. All of our content is written by scientists and people with a strong science background. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. Improve cardiovascular health. Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. In another trial, a combination supplement (Pycnogenol 60 mg/day, L-arginine 690 mg/day and aspartic acid 552 mg/day) improved erectile dysfunction and sexual satisfaction in men after 8 weeks. 1. A 2006 study found that children who took a daily pine bark extract supplement for four weeks had significantly lower levels of hyperactivity. However, it's always a good idea to start with a low dose so you can monitor how your body responds. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. But what makes this miracle ingredient so amazing? You can refer to the National Institutes of Healths dosage guidelines for specific conditions. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. In a study of 33 people with severe osteoarthritis, pycnogenol (200 mg/day) reduced inflammatory markers after 3 weeks. Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78]. A 10 week clinical trial with 30 children shows that Pycnogenol may improve symptoms of Crohns disease. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. Note that the numbers in parentheses (1, 2, etc.) Abdominal pain was by far the most . This key chemical, proanthocyanidin, is also found in high concentrations in apples, cranberries, coca, grapes, and red wine. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. Natural Factors Pycnogenol 25mg 60 Veggie Caps. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. Pycnogenol (pic-noj-en-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and phenolic acids, which offer extensive natural health benefits. Prenatal nutrition can be confusing. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. They could interact with medicines to suppress the immune system, chemotherapy drugs, and blood thinners. 1. In another study, 61 children with ADHD were given one mg per kg/day of Pycnogenol or placebo over four weeks. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. Skin irritation. Studies have also safely used Pycnogenol in children and during pregnancy. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. Healthline Media does not provide medical advice, diagnosis, or treatment. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. (4). Note that each number in parentheses [1, 2, 3, etc.] A trial of 39 people with hay fever found that Pycnogenol may reduce nose and eye symptoms. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. The results showed that the combination of local and systemic applications of Pycnogenol were the best in terms of ulcer healing even though local application of Pycnogenol also speeded up ulcer healing. Taking pine bark extract also increases the blood . Boost gastrointestinal health. In a study of 50 overweight people, a combination product (Pycnogenol, Madeglucyl, and starches called Glucaffect) reduced weight, BMI, blood glucose, and HbA1C after 8 weeks [30]. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? If you knew you could resolve your erectile dysfunction and, therefore, naturally remedy impotence issues, wouldnt you? The staff there can often answer any questions you have and give you more information about specific brands. Our team aims to be not only thorough with its research, but also objective and unbiased. Eliminate blood clots. Research into Pycnogenol has revealed some promising results in over 30 health conditions. Subjects in the study that took Pycnogenol ended up taking fewer painkillers [51]. Moreover, Pycnogenol treatment reduced the use of painkillers. Here are the many health benefits believed to be possible with Pycnogenol: Reduces "leaky" blood vessels by making the wall proteins (collagen, elastin) more resistant to damage. Grape seed extract may be more beneficial for those who are obese. In a study of 76 people with allergic asthma, Pycnogenol (100 mg/day) added to conventional corticosteroid inhalers for 6 months helped 55% of them reduce inhaler use frequency and dosage. Our website services, content, and products are for informational purposes only. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. It also lessened the amount of asthma medication they needed. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. Diabetic retinopathy is a type of eye injury caused by complications from diabetes. Disclaimer: Results are not guaranteed*** and may vary from person to person***. The results of a 2013 animal study suggest that pine bark extract may help to reduce damage to nerve cells following a traumatic brain injury. In this article, well summarize all the potential benefits and the scientific research surrounding pine bark extract and Pycnogenol. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. There are also several other natural ADHD remedies you can try. It also appeared to improve their attention span, visual motor skills, and concentration. It also may help regenerate and maintain vitamin C and E levels while also potentially increasing nitric oxide levels, which may relax and protect blood vessels [1]. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. You should also avoid using pine bark extract without talking to your doctor first if you: You should also do additional research or talk to your doctor before taking pine bark extract if you also take: While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative. Benefits, Nutrition, Uses & How It Compares vs. Blackberries. Last medically reviewed on January 24, 2018. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). Studies have shown that the tree bark can help decrease common symptoms including hot flashes, mood swings, irregular periods, and others. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Pycnogenol health benefits. Speak with your doctor before supplementing. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. High levels of both of these are considered risk factors for heart disease. It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. In combination with Mirtoselect, Pycnogenol may improve blood flow to the eye and reduce eye blood pressure as shown in a trial of 38 people [81]. , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. It also slightly decreased blood pressure and increased testosterone [67]. In long-haul flights, Pycnogenol could be an effective prevention for blood clots. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. During the first month on L-arginine, only five percent of patients experienced normal erection. 4. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. Extracts can also be made from other pine barks, such as Pinus radiata, Pinus densiflora, Pinus thunbergii, and Pinus massoniana. Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. (14, 15). They were treated with 200 mg of Pycnogenol daily or with placebo. Pycnogenol may stimulate the immune system. Pycnogenol seems well-tolerated for use in adults for up to 6 months. This supplement possibly activates the immune system. after four weeks of treatment, Pycnogenol-treated patients showed definite evidence of improved in small blood vessel functions and circulation as compared to those not treated. Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . nausea. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. Pycnogenol is a standardized supplement formula guaranteed to contain at least 65-75% proanthocyanidins, the active . Upset stomach. View as: Grid List. Used early on, it may prevent eye damage and blindness from diabetes [34]. Pycnogenol can help control blood pressure, which helps improve overall heart health. Some small studies suggest it may also protect against coronary artery disease and blood clots. Set Ascending Direction. American Cancer Society: "Pine Bark Extract.". Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. But the actual bioavailability of this complex mixture is still unknown. The outcome showed significant healing when compared to those subjects who were not given any drug or remedy, concluding that Pycnogenol may be an effective remedy for healing of surgery-related lesions. DIM and other plant indoles are found in . Add to Cart. This study adds to a body of research showing the benefits of Pycnogenol . Rating: 100%. Required fields are marked *. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). 3. Typical doses range from 50 milligrams to 450 milligrams per day. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. are clickable links to medically peer-reviewed studies. All rights reserved. Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. SelfDecode does not treat, diagnose or cure any conditions, 2005-2023 Healthline Media a Red Ventures Company. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [19]. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. There havent been any studies looking at long-term liver damage. WebMD does not provide medical advice, diagnosis or treatment. Regardless, a natural option is available and far worth the wait. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. 5) Vein Diseases and Swelling. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Pycnogenol seems to help with asthma and allergies. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. Theres evidence that Pycnogenol may be a promising nootropic for various groups of people, including middle-aged professionals, students, and people with mild cognitive decline like brain fog. Traditionally, people might drink a brew made from pine bark -- rich in pycnogenol -- as a treatment. Early research shows that taking it at least 5 weeks before the start of allergy season seems to lessen symptoms. Cigarette smoking increases platelet aggregation. Interactions. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. A high number signals high blood pressure. All rights reserved. In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. Pycnogenol in metabolic syndrome and related disorders [Abstract]. We take a look at what the science actually says. Most anal fissures heal with home treatment after a few days or weeks. However, this was a relatively small study, so larger ones are needed to fully understand pine bark extracts role in these findings. Some risks associated with Pycnogenol include:, Pycnogenol and other maritime tree barks have not been studied as extensively as traditional medicine. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. Ana has many years of experience in clinical research and health advising. Forty-seven Japanese men with mild erectile dysfunction were given supplementation L-arginine and French maritime pine bark extract over a period of time. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Systolic blood pressure measures how much blood is pumping from your heart to your arteries. Pycnogenol has four main components that contribute to its benefits for men's health. Ana received her MS in Pharmacy from the University of Belgrade. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. Its best to check with your doctor about the dosage, based on the symptoms you have and other possible conditions, prior to taking either pine bark extract or Pycnogenol. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. Various brands of pycnogenol are available. Eye health. returned. 4 Items . Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. ( 4) Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. However, research on these two groups is limited [71, 15]. Pine bark extract has been studied with regard to its ability to help diabetic patients. However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. We avoid using tertiary references. A sitz bath, which involves sitting in warm water for 10 minutes, twice daily, is helpful to patients with anal itching, aching or burning and is known as one of the best ways to get rid of hemorrhoids fast. No side effects were noted, unlike its synthetic counterpart. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. 1) Encourages Healthy Blood Pressure. Dr. Steven Lamm did a great job at explaining the new benefits of pycnogenol. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. Discover what the research says about elimination diets, foods to eat, and more. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. All Pycnogenol-treated patients responded favorably in contrast to placebo treatment. Ask your doctor for advice. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Helps Treat Erectile Dysfunction. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. That said, there are some instances where this extract may possibly be effective. Sort By. Pycnogenol French maritime pine bark extract's 4 basic properties. Pycnogenol was gradually increased to 120 mg/day over this time period, while the l-arginine was maintained at 1.7 g/day throughout. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Researchers suggest that it may have stronger benefits than elastic compression stockings. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD) [Abstract]. These benefits appeared to persist for some time even after stopping supplementation [72]. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. 7. The . Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. There havent been enough studies yet to change practice protocols for treating children. Risks. is a clickable link to peer-reviewed scientific studies. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. Ac., CYT, 12 Benefits of Ginkgo Biloba (Plus Side Effects & Dosage), Tongkat Ali (Eurycoma longifolia): Everything You Need to Know, reduce blood sugar levels in people with diabetes, are within two weeks of a scheduled surgery, medications, herbs, and supplements that affect the blood or clotting. but is for informational and educational purposes alone. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. The list goes on a bit further, as the OPCs in thisextract may inhibit lipid peroxidation, platelet aggregation, capillary permeability and fragility, and to affect enzyme systems, which basically means it may be a natural treatment for many serious health conditions, such as stroke and heart disease.

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